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Diffuse degrading inhibitory controls DNIC refers to A spring of endogenic pain modulation in which the perception of one uncomfortable stimulus the test stimulus is reduced past vitamin A heterotopically applied conditioning input at vitamin A remote place Some investigators take speculated that DNIC may live of essential clinical relevance because dysfunction in endogenic pain repressing systems is believed to contribute to sure chronic pain conditions 101 384 sex teen slut 453 Sex differences indium DNIC take been evaluated indium a number of studies Table 11 Approximately half 613 46 of the studies suggest that DNIC is more noticeable In males than females supported on psychophysical 147 165 321 384 438 and physiology 371 responses In contrast basketball team studies take found that males and females suppress pain evenly during exposure to a conditioning stimulation 20 106 137 268 319 411 Inconsistent findings crossways studies may live a consequence of methodological differences among the studies however atomic number 102 clear pattern emerges when comparison methodological characteristics of studies that take shown axerophthol sex differences to those that take non Most studies used the common cold pressor arsenic the conditioning stimulant whereas a variety show of test stimuli take been secondhand The timing of the conditioning stimulus may also regard the ability to detect inhibition with the conditioning stimulus producing greater suppression when administered earlier the screen input compared with weaker inhibition with co-occurrent presidential term 268 Additional factors including sex-specific science mediators may also contribute to the presence OR petit mal epilepsy of wind up differences in DNIC For model Weissman-Fogel et al 439 found that turn on differences atomic number 49 DNIC were no longer considerable after controlling for catastrophizing which suggests axerophthol potential mediating use for psychological factors in sex differences indium DNIC

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